NCT07109427

Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40,000 (estimated)
• Sponsor: Washington University School of Medicine · Academic / Other
• Sex: Male
• Age: 40 Years – 75 Years
• Healthy volunteers: Accepted

Summary

\- The investigators propose a clinical trial to evaluate the impact of annual shared decision making for PSA screening, supported by system-level enhancements to promote evidence-based care: * Defined referral thresholds within the health maintenance reminder, aligned with clinical risk stratification per NCCN guidelines. * Enhanced clinical decision support (CDS) tools to reduce provider variation and ensure guideline-concordant screening and referral practices. * The goal is to reduce late-stage presentation without increasing overdiagnosis-ensuring that prostate cancer screening is both accessible and clinically effective.

Conditions

• Prostate Cancer
• Cancer of the Prostate

Interventions

Type	Name	Description
OTHER	Annual PSA Health Maintenance Reminder	The annual health maintenance reminder does not mandate PSA screening for eligible patients. Instead, it recommends that primary care providers (PCPs) initiate a shared decision-making discussion with their patients. As part of this conversation, patients will be informed of their individual risk factors-including race, family history, and germline mutations-and can then make an informed choice about whether to proceed with PSA screening.

Timeline

• Start date: 2025-08-11
• Primary completion: 2031-08-31
• Completion: 2031-08-31
• First posted: 2025-08-07
• Last updated: 2025-08-17

Locations

1 site across 1 country: United States