NCT07108803

European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis

European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis (ERGOSTE)

• Status: Enrolling By Invitation
• Phase: —
• Study type: Observational
• Enrollment: 2,500 (estimated)
• Sponsor: Azienda Sanitaria Universitaria Giuliano Isontina (ASU GI) · Unknown
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis (ERGOSTE) is a nascent large surgical registry that would encompass most relevant aspects of IE in Europe in the contemporary era.

Detailed description

ERGOSTE, Purposes: * To create a European multicenter retrospective database including a large number of patients undergoing surgical treatment for infective endocarditis (IE). * To perform epidemiologic analyses of IE-patients and involved pathogens. * To find independent predictors of early post-operative death. * To test ALL the scoring systems specifically developed to predict early death after surgery for infective endocarditis. * To devise a specific risk score for early postoperative death. * To explore early and late outcomes of these very difficult patients in order to establish optimal indications, techniques and timing of surgery. * To carry out a number of sub-analyses concerning the demographic parameters and variable clinical presentation of patients, type and severity of cardiac structural involvement, adopted valve prostheses and surgical techniques, and different involved microbiologic agents. * To lay experiential foundations of a prospective database on the topic.

Conditions

• Infective Endocarditis (IE)

Timeline

• Start date: 2025-06-01
• Primary completion: 2025-08-31
• Completion: 2025-08-31
• First posted: 2025-08-07
• Last updated: 2025-08-07

Locations

1 site across 1 country: Italy