NCT07107165

Psychosocial and Behavioral Intervention for Stem Cell Transplant Patients and Their Family Caregivers

Adapting After Discharge From Allogeneic SCT: Partnering Together; Dyadic Intervention to Improve Patient-Family Caregiver Team-Based Management of the Medical Regimen After Allogeneic Hematopoietic Cell Transplantation

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 208 (estimated)
• Sponsor: University of Pittsburgh · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Adherence to the medical regimen after stem cell transplant is challenging for both patients and their family caregivers. The investigators propose a randomized clinical trial testing two brief psychosocial interventions to determine if either improves patient and family caregiver psychosocial and health-related outcomes.

Detailed description

The investigators propose a randomized controlled trial testing two brief, 4 session psychosocial interventions to help patients and family caregivers better manage the time period after hospital discharge from stem cell transplant. Patients and family caregivers will be randomized to either the skill learning intervention (n=52 patient-family caregiver dyads) or to the supportive care intervention (n=52 patient-family caregiver dyads). The intervention will be conducted via live video conferencing. Patients and family caregivers will complete questionnaires before the intervention and at 1-, 5-, 12-, 24 weeks afterwards. The investigators will determine whether the skills learning group has improved outcomes, including adherence to the medical regimen and perceived task efficacy.

Conditions

• Stem Cell Transplant
• Hematopoetic Stem Cell Transplant
• Hematopoetic Stem Cell Transplantation

Interventions

Type	Name	Description
BEHAVIORAL	Dyadic Problem Solving Training	DPST consists of teaching the patient and family caregiver problem-solving skills that they can apply to help them manage the medical regimen after stem cell transplant.
BEHAVIORAL	Supportive Care	Supportive Care consists of providing support to the patient and family caregiver as they manage the medical regimen after stem cell transplant

Timeline

• Start date: 2025-07-01
• Primary completion: 2027-06-01
• Completion: 2027-07-01
• First posted: 2025-08-06
• Last updated: 2026-04-01

Locations

1 site across 1 country: United States