NCT07106281

Chronic Grape Extract in Crosstraining Athletes: A Randomized Crossover Trial

Effect of Chronic Grape Extract Supplementation in Trained Cross-training Athletes: A Randomized, Triple-blinded, Placebo-Controlled Crossover Study

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Universidad de Granada · Academic / Other
• Sex: Male
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to investigate the effect of cronic GSE intake in crosstraining may have a favorable impact on biochemical markers, recovery, and performance.

Detailed description

Supplementation with certain antioxidant nutrients is a feasible strategy to accelerate recovery from fatigue and prevent exercise-induced oxidative damage. Grape seed extract (GSE) contains flavonoids such as proanthocyanidins, which are potent antioxidants with numerous health benefits. Therefore, optimizing the recovery process after training is essential for athletes engaged in strength and power sports who aim to enhance performance. Thirty trained CrossFit athletes consumed grape seed extract or a placebo for one week. The training session consisted of a 12-minute strength block, a 13-minute metabolic conditioning (MetCon), and a final 15-minute MetCon. The Rating of Perceived Exertion (RPE), Gastrointestinal Distress Score (GDS), blood pressure and the Perceived Recovery Status scale (RPS) were administered at the beginning of the session and at the end of each segment of the CrossFit session. DOMS was assessed using a visual analog scale at 24 and 48 hours after the CrossFit session.

Conditions

• Performance

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Grape Seed Extract	600mg of Grape Seed Extract
DIETARY_SUPPLEMENT	Placebo	Placebo

Timeline

• Start date: 2025-09-01
• Primary completion: 2025-12-20
• Completion: 2026-01-31
• First posted: 2025-08-06
• Last updated: 2025-08-06

Locations

1 site across 1 country: Spain