NCT07103915

Intranasal Lidocaine Spray Versus Nasogastric Tube Administration in the Emergency Room

Patient Satisfaction and the Effectiveness of Intranasal Lidocaine Spray Versus Nasogastric Tube Administration in the Emergency Room

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Ankara City Hospital Bilkent · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to evaluate whether 10% intranasal lidocaine spray reduces pain and improves the success rate of nasogastric tube (NGT) insertion compared to placebo in adult emergency department patients. The study's primary outcomes were: Procedure success rate (first-pass success) Pain during insertion, measured by the Numeric Rating Scale (NRS), where 0 = "no pain" and 10 = "worst possible pain". The secondary outcomes included: Duration of the procedure (in seconds) Overall success rate (eventual successful insertion regardless of attempts) Pain score at the 5th minute post-procedure (NRS) Patient preference for the same method in future procedures (yes/no) Procedure satisfaction, assessed using an NRS-based score from 0 ("not satisfied at all") to 10 ("completely satisfied"). Participants were randomized to receive either lidocaine or placebo spray intranasally before standard NGT insertion. Pain, success rate, and satisfaction were compared between groups.

Detailed description

This randomized controlled trial aims to evaluate the effect of intranasal lidocaine 10% spray on patient comfort and pain during nasogastric tube (NGT) insertion in the emergency department. NGT placement is often associated with significant discomfort and anxiety, which can reduce procedural success and patient cooperation. Eligible adult patients requiring nasogastric tube insertion in the emergency setting will be randomly assigned to receive either intranasal lidocaine spray or a placebo spray prior to the procedure. Both groups will undergo standard NGT placement performed by emergency physicians. The primary outcome of the study is the level of pain experienced during the procedure, assessed using the Visual Analog Scale (VAS). Secondary outcomes include patient satisfaction, ease of tube placement from the clinician's perspective, vital signs during the procedure, and any adverse effects related to the spray or procedure. The study seeks to determine whether intranasal lidocaine spray improves procedural comfort and increases overall satisfaction during a commonly performed yet unpleasant emergency intervention.

Conditions

• Nasogasrtic Tube Insertion

Interventions

Type	Name	Description
DRUG	Lidocaine 10% Spray	This study evaluates whether intranasal 10% lidocaine spray reduces pain and improves first-pass success during nasogastric tube (NGT) insertion compared to placebo.
OTHER	Placebo	Drug: Placebo Spray (Ethanol-matched solution without lidocaine)

Timeline

• Start date: 2023-11-01
• Primary completion: 2024-06-30
• Completion: 2024-08-15
• First posted: 2025-08-05
• Last updated: 2025-08-05

Locations

1 site across 1 country: Turkey (Türkiye)