NCT07099872

Chronic Exercise With Overdressing

Efficacy of a Novel Exercise + Overdressing Protocol to Induce Heat Acclimation in Temperate Environments (Chronic XO-Study)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: United States Army Research Institute of Environmental Medicine · Federal
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine if five training sessions of exercise with overdressing can induce heat acclimation.

Detailed description

Twelve healthy and fit adults will complete 90 min of exercise (6.0 mph run for 30 min followed by 3.5 mph walk for 60 min) on five occasions at room temperature (\~20 °C, 50% RH, 1 mph air velocity). Participants will be randomized into either the exercise with overdressing or exercise wearing standard physical training (PT) clothing group and complete the study in a crossover manner. Heat acclimation induction will be assessed using standardized heat stress tests (HSTs) performed before and after five training sessions. After the final HST has occurred, participants will complete a minimum 4-week washout and then return to repeat the identical protocol in the opposite configuration (overdressing vs. PT clothing). The investigators hypothesize that, compared to 5 days of exercise in PT clothing, 5 days of exercise with overdressing will lower end-exercise core temperature during standardized HSTs.

Conditions

• Heat Acclimation and Thermotolerance

Interventions

Type	Name	Description
OTHER	Control	Wear normal attire (shorts/t-shirt) during exercise sessions in a gym-like environment.
OTHER	Overdressing	Wear standardized overdressing ensemble during exercise sessions in a gym-like environment.

Timeline

• Start date: 2024-10-28
• Primary completion: 2025-05-05
• Completion: 2025-05-05
• First posted: 2025-08-01
• Last updated: 2025-08-01

Locations

1 site across 1 country: United States