NCT07099404

Parathyroid Adenoma Detection With Rubidium-82 Imaging

Parathyroid Adenoma Detection With Rubidium Chloride Imaging: A Proof-of-Concept Study

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 20 (estimated)
• Sponsor: Matthieu Pelletier-Galarneau, MD MSc · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Assess the uptake of rubidium-82 in parathyroid adenomas.

Detailed description

Parathyroid adenomas demonstrate uptake of rubidium-82 chloride and can be detected with PET imaging. The investigators aim to describe the uptake pattern of rubidium-82 chloride in parathyroid adenomas as well as compare the uptake pattern of rubidium-82 chloride to that of 18F-fluorocholine in patients with parathyroid adenoma.

Conditions

• Parathyroid Adenomas
• Hyperparathyroidism, Primary

Interventions

Type	Name	Description
OTHER	PET/CT imaging with rubidium-82	PET imaging of the neck will be started immediately before infusion of 10 Megabecquerels per kilograms of rubidum-82 over 30 seconds. The acquisition will last 10 minutes. This will be followed by a non-contrast low-dose CT of the neck for localization and attenuation correction.

Timeline

• Start date: 2025-11-01
• Primary completion: 2027-09-01
• Completion: 2028-09-01
• First posted: 2025-08-01
• Last updated: 2025-08-22

Locations

2 sites across 1 country: Canada