NCT07098533

Cognicise Training for Seniors for Healthy Aging

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Poznan University of Physical Education · Academic / Other
• Sex: Female
• Age: 65 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to assess the impact of two 8-week motor-cognitive exercise programs - Cognicise and yoga - on psychological, respiratory, cardiovascular, postural, and biochemical health in elderly women. The main objectives are to evaluate whether these programs: Improve psychological parameters such as mood, quality of life, depressive symptoms, and cognitive abilities; Enhance respiratory function, including lung volumes and ventilation; Influence cardiovascular parameters such as blood pressure and heart rate; Improve chest mobility, physical fitness, and cardiorespiratory capacity; Induce favorable changes in selected blood biomarkers, including neurotrophic factors, hormones, glucose, lipids, and blood morphology; Improve postural stability, as assessed through posturographic analysis. The study compares the effects of yoga and Cognicise to a control group that does not receive any intervention. Participants in the yoga and Cognicise groups will take part in supervised sessions twice a week for 8 weeks (each session lasting 45 minutes). Participants from all three groups (yoga, Cognicise, and control) will undergo pre- and post-intervention assessments, including: Psychological questionnaires; Spirometry and cardiorespiratory tests; Blood pressure and heart rate measurements; Chest mobility and physical fitness tests; Posturographic assessment of postural control during quiet standing with eyes open and closed; Laboratory blood tests (including BDNF, GDNF, 25(OH)D, TSH, testosterone, cortisol, insulin, glucose, lipid profile, and complete blood count with differential). The aim is to determine whether structured motor-cognitive training leads to measurable health benefits compared to no intervention.

Conditions

• Depressive Symptom
• Cognitive Functions
• Quality of Life
• Physical Fitness
• Blood Biomarkers
• Elderly (People Aged 65 or More)
• Postural Stability
• Fall Risk
• Postmenopausal Women
• Cardiopulmonary

Interventions

Type	Name	Description
BEHAVIORAL	Cognicise Training	The Cognicise program included 16 sessions over 8 weeks (twice weekly, 60 minutes each). This dual-task training combined motor activities with cognitive exercises. During basic gymnastic movements, participants responded to real-time changes in live music and visual stimuli while also solving simple verbal and math tasks. Sessions were divided into 15 minutes of warm-up, 30 minutes of dual-task activity, and 15 minutes of breathing and relaxation exercises.
BEHAVIORAL	Yoga Training	The yoga intervention consisted of 16 instructor-led sessions over 8 weeks (twice weekly, 60 minutes each). Each session included a warm-up (15 minutes), a main phase (30 minutes) focused on exercises targeting the spine, pelvis, and hips, and a relaxation period (15 minutes), including 10 minutes of deep relaxation techniques.

Timeline

• Start date: 2023-04-04
• Primary completion: 2023-06-21
• Completion: 2023-06-21
• First posted: 2025-08-01
• Last updated: 2025-08-01

Locations

1 site across 1 country: Poland