Trials / Not Yet Recruiting
Not Yet RecruitingNCT07094958
Efficacy of Stromal Vascular Fraction on Acne Scar Correction
Efficacy of Intradermal Stromal Vascular Fraction Injection in the Treatment of Atrophic Acne Scar
- Status
- Not Yet Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 16 (estimated)
- Sponsor
- Seoul National University Hospital · Academic / Other
- Sex
- All
- Age
- 19 Years – 45 Years
- Healthy volunteers
- Not accepted
Summary
This study aims to evaluate the efficacy and safety of intradermal injection of autologous stromal vascular fraction (SVF) in the treatment of atrophic acne scars. SVF is a heterogeneous cell population derived from adipose tissue, containing various regenerative and immunomodulatory cells, including mesenchymal stem cells, endothelial progenitor cells, and pericytes. In this prospective, randomized, split-face clinical trial, participants with atrophic acne scars will receive SVF injections on one side of the face and normal saline (NS) injections on the contralateral side as a control. Clinical efficacy will be assessed through blinded scar counts, digital imaging, and histological evaluations including epidermal and dermal regenerative markers. The study is designed to investigate whether SVF provides superior clinical improvement compared to placebo.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | stromal vascular fraction (SVF) | Autologous stromal vascular fraction (SVF) isolated from adipose tissue was injected intradermally into one side of the face to evaluate its efficacy in treating atrophic acne scars. SVF was freshly prepared on the same day of injection using enzymatic digestion and centrifugation. |
| OTHER | Normal Saline (NS) | Normal saline (NS) was injected intradermally into the contralateral side of the face and served as a placebo comparator to SVF in this split-face study on atrophic acne scars. |
Timeline
- Start date
- 2025-07-01
- Primary completion
- 2025-12-01
- Completion
- 2026-07-01
- First posted
- 2025-07-31
- Last updated
- 2025-07-31
Source: ClinicalTrials.gov record NCT07094958. Inclusion in this directory is not an endorsement.