NCT07094646

Full Assessment of Clinical Transfusion Support

An Assessment of Hematologic Diseases Among Blood Transfusion Recipients and Donated Units at a Pediatric Regional Referral Hospital in Uganda

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 250 (actual)
• Sponsor: Children's Hospital Medical Center, Cincinnati · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

This study looks at why some children develop very severe anemia that leads to a blood transfusion. It also checks for diseases in the blood they receive. Researchers are using small samples of dried blood (called dried blood spots) from both the children and the donated blood to find out what might be causing the anemia.

Detailed description

This study includes children at Jinja Regional Referral Hospital (Jinja, Uganda) who need a blood transfusion, whether they are in the clinic, emergency room, or children's ward. After doctors finish the usual blood tests, a small sample of leftover blood will be saved on a special card (called a dried blood spot). The same will be done for all blood transfused during the study. These samples will be frozen and later sent to Cincinnati Children's Hospital for testing.

Conditions

• Sickle Cell Anemia
• Blood Transfusion
• Malaria Parasitaemia

Timeline

• Start date: 2023-09-21
• Primary completion: 2024-03-19
• Completion: 2024-03-19
• First posted: 2025-07-30
• Last updated: 2025-07-30

Locations

1 site across 1 country: Uganda