NCT07091097

Multivisceral Oncological Resections Involving the Pancreas - An International Multicenter Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,283 (actual)
• Sponsor: Martin-Luther-Universität Halle-Wittenberg · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Background: Complete resection is the primary curative option for most non-metastatic solid malignancies. Locally advanced stages, involving adjacent organs or structures, may require multivisceral resection. This study aims to comprehensively assess outcomes and risk factors of multivisceral oncological resections involving the pancreas, enhance understanding, and provide clinical guidance. The potential establishment of an international study group, centered on multivisceral resections involving the pancreas, will be further pursued based on the insights derived from this study. Objective: The objective of this study is to evaluate the outcomes of multivisceral oncological resections involving the pancreas and identify predictive factors for morbidity/mortality as well as for overall and disease-free survival. Methods: This retrospective multicenter study involves centers on a global scale conducting multivisceral oncological resections involving the pancreas. Data will be collected retrospectively from January 1st, 2010 to December 31st, 2022. Eligible patients are those undergoing elective multivisceral oncological resections involving the pancreas. Patient and operation characteristics, perioperative therapies, outcomes, complications, resection margins, and survival are recorded. Statistical analysis includes appropriate tests and subgroup analyses for distinct tumor entities.

Conditions

• Pancreatic Cancer
• Multivisceral Pancreatic Resections

Timeline

• Start date: 2024-01-01
• Primary completion: 2025-06-30
• Completion: 2025-06-30
• First posted: 2025-07-29
• Last updated: 2025-07-29

Locations

1 site across 1 country: Germany