NCT07091032

Building Connections

Building Connections Between Practices, Patients, and Community Health

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 3,600 (estimated)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Building Connections seeks to address health and healthcare inequities in socially vulnerable communities. The project will be conducted in collaboration with clinical practices across Massachusetts, serving a diverse population heavily represented in Community Clinics and Health Centers. The program will offer evidence-based interventions in obesity/weight management, cancer screening, and mental health.

Conditions

• Cancer Colorectal
• Cancer Cervix
• Depression, Anxiety
• Obesity

Interventions

Type	Name	Description
OTHER	Treatment as Usual	This is the comparison condition, in which participants will receive treatment as usual for their conditions at the clinic.
BEHAVIORAL	Building Connections Intervention	The combined Building Connections intervention incorporates three areas. Participants take part in those for which they are eligible. The obesity/weight management intervention offers coaching and support for education on evidence-based anti-obesity medications (AOM) and a lifestyle behavioral intervention offered by Community Health Workers focused on diet and physical activity. The cancer screening intervention focuses on developing workflows and systems to offer a CHW-delivered population-based intervention to improve colorectal and cervical cancer, focusing on newer screening modalities and monitoring adherence for individuals with a positive screening test result. The mental health intervention uses the evidence-based Strong Minds intervention, a 10-session psychoeducational program provided by trained community health workers with clinical supervision. The skills-based intervention uses an integrative approach aimed at improving depression, anxiety, and trauma-related symptoms.

Timeline

• Start date: 2025-08-07
• Primary completion: 2029-12-30
• Completion: 2029-12-30
• First posted: 2025-07-29
• Last updated: 2025-11-18

Locations

1 site across 1 country: United States