Trials / Recruiting
RecruitingNCT07090941
EVT in Acute Basilar Artery Occlusion With Large Infarction Core
Trial of Endovascular Treatment in Acute Basilar Artery Occlusion Patients With a Large Infarct Core
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 348 (estimated)
- Sponsor
- The First Affiliated Hospital of Hainan Medical University · Other Government
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
A multicenter, prospective, open-label, blinded endpoint, randomized controlled trial designed to evaluate the efficacy and safety of best medical management (BMM) combined with endovascular treatment (EVT) versus BMM alone in acute basilar artery occlusion (BAO) patients with large infarct cores.
Detailed description
This trial aims to evaluate whether best medical management (BMM) combined with endovascular treatment (EVT) versus BMM alone improves neurological outcomes in acute basilar artery occlusion (BAO) patients with large infarct cores. A centralized 1:1 simple randomization design assigns participants to receive either EVT or BMM based on randomization results.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Endovascular Treatment | The vascular access route is selected based on the patient's anatomical characteristics and operator discretion. Endovascular treatment (EVT) procedures must adhere to each participating center's standardized operating protocols. Upon confirmation of vascular occlusion, EVT may be performed using devices approved by China's National Medical Products Administration (NMPA). Based on lesion-specific features and operator judgment, permissible techniques include stent retriever thrombectomy, aspiration thrombectomy, balloon angioplasty with or without stenting, or intra-arterial thrombolysis. Investigational devices are strictly prohibited. |
Timeline
- Start date
- 2025-08-01
- Primary completion
- 2027-09-30
- Completion
- 2027-12-31
- First posted
- 2025-07-29
- Last updated
- 2025-07-29
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT07090941. Inclusion in this directory is not an endorsement.