Clinical Trials Directory

Trials / Recruiting

RecruitingNCT07090785

A Study of LY4088044 in Healthy Participants

A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single- and Multiple-Ascending Dose Study to Characterize the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY4088044 in Healthy Participants.

Status
Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
104 (estimated)
Sponsor
Eli Lilly and Company · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to evaluate how well LY4088044 is tolerated and what side effects may occur in healthy participants. The study drug will be administered either subcutaneously (SC) (under the skin) or intravenously (IV) (into a vein in the arm). Blood tests will be performed to check how much LY4088044 gets into the bloodstream and how long it takes the body to eliminate it. The study will last up to approximately 92 weeks for Parts A, B, and C, excluding screening.

Conditions

Interventions

TypeNameDescription
DRUGLY4088044Administered IV
DRUGLY4088044Administered SC
DRUGPlaceboAdministered IV
DRUGPlaceboAdministered SC

Timeline

Start date
2025-07-24
Primary completion
2027-07-01
Completion
2027-07-01
First posted
2025-07-29
Last updated
2026-03-02

Locations

6 sites across 3 countries: United States, New Zealand, Singapore

Regulatory

Source: ClinicalTrials.gov record NCT07090785. Inclusion in this directory is not an endorsement.