NCT07089498

13C-Octanoic Acid Breath Test on Gastric Emptying in Celiac Patients With Functional Disorders

13C-Octanoic Acid Breath Test for the Evaluation of a Low-fodmaps Diet on Gastric Emptying in Celiac Patients With Functional Disorders

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 68 (actual)
• Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this interventional study is the evaluation of a diet low in fodmaps on gastric emptying in celiac patients with functional disorders.

Detailed description

The goal of this interventional study is the evaluation of a diet low in fodmaps on gastric emptying in celiac patients with functional disorders. The aims of the study are: * Evaluation of gastric emptying time by a 13C-Octanoic Acid Breath Test, pre and post-diet (T1 and T2) in celiac patients with functional dyspepsia and non-celiac patients with functional dyspepsia. * Evaluation of gastrointestinal symptoms, quality of life, and mental health in patients with non-celiac and celiac functional disorders pre- and post-diet (T1 and T2). Participants: * Will run the 13C-octanoic acid breath test pre- and post-diet * Will complete the VAS, SF-36, and SCL-90 questionnaires pre- and post-diet * Will follow a low fodmap gluten free diet or a regular gluten-free diet for six weeks Researchers will compare celiac and non-celiac patients.

Conditions

• Functional Gastrointestinal Disorders

Interventions

Type	Name	Description
OTHER	Dietary Intervention (Low Fodmap Gluten Free Diet)	The intervention provides the administration of a Low Fodmap Diet to celiac or non celiac patients with functional gastrointestinal disorders

Timeline

• Start date: 2021-02-03
• Primary completion: 2023-11-30
• Completion: 2024-04-30
• First posted: 2025-07-28
• Last updated: 2025-07-28

Locations

2 sites across 1 country: Italy