NCT07089459

Low Level Laser Therapy Versus Short Wave Diathermy in Patients With Anterior Cruciate Ligament Tear

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 72 (actual)
• Sponsor: University of Lahore · Academic / Other
• Sex: All
• Age: 20 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

This clinical research study is comparing two non-surgical treatments-Low-Level Laser Therapy (LLLT) and Short Wave Diathermy (SWD)-to see which is more effective for people with a partial tear of the anterior cruciate ligament (ACL) in the knee. The ACL is a key ligament that helps keep the knee stable during movement. When partially torn, it can cause pain, weakness, and difficulty with walking or physical activities. LLLT, also called photobiomodulation, is a painless, light-based therapy that helps reduce swelling, relieve pain, and promote healing. SWD is a type of deep heat therapy commonly used in physiotherapy to improve circulation and tissue repair. This study will include 72 patients between 20 and 40 years old who have been diagnosed with a partial ACL tear through MRI. All participants will receive standard physiotherapy exercises and SWD, while half will also receive LLLT. The study aims to find out if adding LLLT can: Reduce knee pain Improve knee muscle strength Help patients perform daily activities more easily Each participant will be monitored for 6 weeks, with check-ins at the start, the 3rd week, and the 6th week. Pain levels, muscle strength, and knee function will be measured using reliable assessment tools. The results of this study may help guide better treatment options for people with ACL injuries who want to avoid surgery.

Detailed description

Background \& Rationale: Partial anterior cruciate ligament (ACL) tears are frequent orthopedic injuries, particularly among young adults involved in sports requiring rapid pivoting or directional changes. These injuries often result in pain, instability, muscular weakness, and functional limitations. While complete ACL tears often necessitate surgical reconstruction, partial tears are typically managed with conservative approaches such as physiotherapy and adjunctive non-invasive therapies. Low-Level Laser Therapy (LLLT), or photobiomodulation, is a non-thermal modality that promotes tissue healing through light-induced cellular stimulation. It has shown beneficial effects in reducing inflammation and pain across various musculoskeletal conditions. However, there is limited high-quality evidence evaluating its specific effects on partial ACL injuries or how it compares to widely used modalities like Short Wave Diathermy (SWD). Study Design and Methodology: This is a single-blinded, randomized controlled trial enrolling 72 participants aged 20-40 years with MRI-confirmed partial ACL tears. Participants are randomly assigned (n=36 each) into two groups: Group A (LLLT + SWD + Physiotherapy): Receives Low-Level Laser Therapy in addition to standard physiotherapy and short wave diathermy Group B (SWD + Physiotherapy): Receives standard physiotherapy and short wave diathermy only LLLT Protocol: Wavelength: 830 nm Power Output: 150 mW Power Density: 5 W/cm² Frequency: 2-3 sessions per week for 6 weeks Application Time: 3-4 minutes per treatment site (targeting multiple anatomical points around the knee) Standard Physiotherapy for Both Groups: Exercises: Heel slides, partial knee bends, quadriceps sets, step-ups Repetitions: 2 sets of 10, with 3-5 second rest intervals Short Wave Diathermy Protocol (Both Groups): Frequency: 27.12 MHz Duration: 20-30 minutes per session Application: 2-3 sessions over baseline phase Outcome Measures: Assessments will be conducted at baseline, 3rd week, and 6th week using validated clinical tools: Pain: McGill Pain Questionnaire Muscle Strength: Handheld dynamometer (quadriceps/hamstrings) Functional Disability: KOOS (Knee Injury and Osteoarthritis Outcome Score) Blinding and Randomization: Random allocation via computerized random number generation Single-blinded: Outcome assessors blinded to group assignment Ethical Approval and Consent: Approved by the Ethical Review Committee at the University of Lahore Informed written consent obtained from all participants Privacy and confidentiality strictly maintained Expected Impact: This study aims to provide evidence on whether LLLT offers superior clinical outcomes in pain relief, strength enhancement, and functional recovery compared to SWD in the conservative management of partial ACL injuries. The findings may help refine treatment protocols, promote cost-effective and non-invasive rehabilitation options, and guide physiotherapists in evidence-based practice.

Conditions

• Anterior Cruciate Ligament (ACL) Tear

Interventions

Type	Name	Description
DEVICE	Low-Level Laser Therapy (LLLT)	Low-Level Laser Therapy (LLLT) will be administered using an 830 nm wavelength and 150 mW power output with 5 W/cm² power density. The laser probe will be applied 2-3 times per week for 6 weeks over the affected knee. Treatment is performed using a direct skin contact method with 3-4 minutes of exposure per point around the knee joint. The goal is to reduce inflammation, enhance collagen synthesis, and support ligament healing in patients with partial anterior cruciate ligament (ACL) tears. This intervention is provided in addition to standard physiotherapy and shortwave diathermy.
BEHAVIORAL	Shortwave therapy	Participants in this group will receive standard physiotherapy exercises combined with shortwave diathermy (SWD), without the application of Low-Level Laser Therapy (LLLT). The exercise protocol includes heel slides, supported partial knee bends, quadriceps sets, and step-ups, performed in 2 sets of 10 repetitions with 3-5 second rest intervals. SWD will be delivered 2-3 times, using a 27.12 MHz frequency for 20-30 minutes per session, targeting pain relief and enhanced soft tissue healing. This group functions as an active comparator to assess the additional therapeutic value of LLLT used in the intervention group.

Timeline

• Start date: 2024-10-15
• Primary completion: 2025-06-19
• Completion: 2025-07-15
• First posted: 2025-07-28
• Last updated: 2025-08-03

Locations

1 site across 1 country: Pakistan