NCT07088900

The Effectiveness of Dexmedetomidine as an Adjuvant for Bupivacaine Caudal Block in Pediatric Open Appendectomy Under General Anesthesia

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 2 Years – 7 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate if adding dexmedetomidine to bupivacaine in a caudal block can provide longer and better quality pain relief for children after open appendectomy surgery. The study will also assess the effect of this combination on the quality of recovery, including the incidence of emergence delirium, and its overall safety profile.

Conditions

• Appendectomy
• Pediatric

Interventions

Type	Name	Description
PROCEDURE	caudal block using dexmedetomidine with bupivacaine	Patients will receive a single-shot caudal block with 1 mL/kg of 0.25% bupivacaine mixed with 1 µg/kg of dexmedetomidine (diluted in 1 mL of normal saline).
PROCEDURE	caudal block with bupivacaine	Patients will receive a single-shot caudal block with 1 mL/kg of 0.25% bupivacaine mixed with 1 mL of normal saline

Timeline

• Start date: 2025-08-01
• Primary completion: 2025-10-31
• Completion: 2025-11-30
• First posted: 2025-07-28
• Last updated: 2025-09-04

Locations

1 site across 1 country: Egypt