Trials / Recruiting
RecruitingNCT07088874
Novel Biomarkers and Postoperative Kidney Injury in Radical Nephrectomy
Novel Biomarkers to Predict Acute Kidney Injury and Chronic Kidney Disease After Radical Nephrectomy: an Exploratory Prospective Cohort Study
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 60 (estimated)
- Sponsor
- Peking University First Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The incidence of acute kidney injury (AKI) after radical nephrectomy exceeds 40%. Currently, the KDIGO criteria are the recognized diagnostic standard for AKI. These criteria primarily use serum creatinine and urine output as key indicators, but both parameters have certain limitations, such as delayed response, insensitivity, and inaccuracy. This study aims to simultaneously monitor perioperative novel renal damaging, stressful, and functional biomarkers in patients undergoing radical nephrectomy, and to investigate their predictive value for AKI and postoperative 1-year chronic kidney disease (CKD).
Conditions
Timeline
- Start date
- 2025-08-02
- Primary completion
- 2026-07-30
- Completion
- 2027-07-30
- First posted
- 2025-07-28
- Last updated
- 2025-09-08
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT07088874. Inclusion in this directory is not an endorsement.