NCT07088276

Microneedling Combined With Topical Crisaborole 2 % Ointment in Treatment of Vitiligo.

Microneedling Combined With Topical Crisaborole 2 % Ointment in Treatment of Vitiligo. A Prospective Controlled Trial.

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to learn if topical crisaborole ointment works to treat vitiligo. It will also learn about the safety of the drug. The main questions it aims to answer are: Can the drug cause repigmentation of vitiligo lesions when used as topical form after microneedling? What medical problems do participants have when the drug used? Participants will: Visit the clinic once every 2 weeks to have the microneedling sessions for 3 months. and also they will have narrow band UVB sessions two times per week. Record any side effect they have during or after the sessions.

Conditions

• Vitiligo

Interventions

Type	Name	Description
PROCEDURE	microneedling with topical crisaborole	From each patient 3 patches will be selected The first will have microneedling and topical crisaborole and NB UVB sessions The second will have microneedling and NB UVB sessions The third will be exposed only to NB UVB sessions The microneedling sessions will be every 2 weeks for 6 sessions

Timeline

• Start date: 2025-08-01
• Primary completion: 2026-03-01
• Completion: 2026-08-01
• First posted: 2025-07-28
• Last updated: 2025-07-30