NCT07084948

Using Flavonoids to Kill Hepatitis B Virus

Composition for Treating Acute Hepatitis, Chronic Hepatitis, Cirrhosis, and Hepatocellular Carcinoma for Hepatitis B Virus (SB Flavon)

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 134 (actual)
• Sponsor: Trieu, Nguyen Thi, M.D. · Individual
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The composition treats Acute Hepatitis, Chronic Hepatitis, Cirrhosis, and hepatocellular carcinoma (S.B.Flavonoids) at an early stage. The product is ascorbic acid, L-Arginine hydrochloride, Kaempferol, Urinariaflavone, 5,6-dihydroxy-7,8,4'-trimethoxy-flavone, Quercetin, and Rutin. These components have participated in protecting liver cell membranes, focusing on reducing liver stress and supporting their structure, repairing and regenerating new liver parenchyma, preventing fibrosis cell generation, and preventing liver cancer cell growth at an early stage. The composition supplements precursors that help the body strengthen antibodies and reduce the risk of inflammation, and restore the physiological and biochemical functions of liver cells after chronic inflammation.

Detailed description

The product is Acid ascorbic, L-Arginine hydrochloride, Kaempferol, Urinariaflavone, 5,6-dihydroxy-7,8,4'-trimethoxy-flavone, Quercetin, Rutin as the key compounds in the regeneration of to protect liver cell membranes, focus on reducing liver stress and supporting their prevent structure, fibrosis liver cell fibrosis, removing scar tissue, stimulate and release growth hormones, prevent progression to HCC, and prevent HCC recurrence. The pharmaceutical ingredients involved in the composition are calculated to increase their effectiveness in preventing and curing acute hepatitis, chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Currently, many preparations have been and are being studied to fight against acute hepatitis, chronic hepatitis, cirrhosis, and liver cancer globally. The effectiveness of this preparation is a new finding that has been proven over 8 years of follow-up. This ingredient is used as a supplement to stabilize the endothelium, regulate the amount of cortisol within normal limits, and help the body produce B lymphocytes with a good response. Acid ascorbic, L-Arginine hydrochloride, Kaempferol, Urinariaflavone, 5,6-dihydroxy-7,8,4'-trimethoxy-flavone, Quercetin, Rutin. Flavonoids participate in cell protection against toxic proteins, which are produced during prolonged inflammation, blocking the action and removing denatured proteins that change the parenchyma of liver cells. The selected flavonoids repaired the fibrotic structure of liver parenchyma after chronic inflammation. Ascorbic acid and L-arginine help to facilitate biological functions in cell adhesion, synergize with flavonoids in cell membrane protection, structural repair, and liver cell regeneration.

Conditions

• Hepatitis B Virus Infection

Interventions

Type	Name	Description
DRUG	Flavonoid	The daily maintenance, Tenofovir 150mg + SB Flavon 1345mg dose is to be taken 2 times a day, 1 tablet each time. The composition treats acute hepatitis, chronic hepatitis, cirrhosis, and hepatocellular carcinoma at an early stage. The product is Acid ascorbic, L-Arginine hydrochloride, Kaempferol, Urinariaflavone, 5,6-dihydroxy-7,8,4'-trimethoxy-flavone, Quercetin, Rutin. Use these ingredients to protect liver cell membranes, preventing the growth of HBV in the body.
DRUG	Tenofovir	The daily maintenance, Tenofovir 300mg dose is to be taken 1 time a day, 1 tablet each time. The composition treats acute hepatitis, chronic hepatitis, cirrhosis, and hepatocellular carcinoma.

Timeline

• Start date: 2015-11-30
• Primary completion: 2021-10-10
• Completion: 2025-06-20
• First posted: 2025-07-25
• Last updated: 2025-09-11

Locations

2 sites across 2 countries: United States, Vietnam

Regulatory

• FDA-regulated drug study