NCT07084792

Dynamic Motor Cortical Responses to Subdural Electrical Stimulation.

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Medical University of South Carolina · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to better understand how subdural electrical stimulation of the brain affects motor cortical oscillations

Detailed description

Direct cortical stimulation (DCS) has shown the potential to improve symptoms in patients with Parkinson's disease, however its effects have not been consistent in randomized studies to date, limiting widespread adoption of this technology. A critical gap in our knowledge is a detailed understanding of how DCS affects motor areas in the brain. Investigators propose using subdural DCS (sDCS) while simultaneously recording directly from motor cortex using subdural electrocorticography (sECoG) in patients undergoing deep brain stimulation surgery. Investigators expect this novel approach to broaden our understanding of sDCS application and possibly lead to therapeutic advances in this population.

Conditions

• Parkinsons Disease (PD)

Interventions

Type	Name	Description
DEVICE	Direct cortical stimulation	Stimulation

Timeline

• Start date: 2025-08-16
• Primary completion: 2025-08-16
• Completion: 2025-08-16
• First posted: 2025-07-25
• Last updated: 2025-08-22