NCT07084194

Impact of Integrating Two Nano Based Irrigants With Two Activation Techniques in Treatment of Teeth With Acute Pulpitis on Postoperative Pain and Flare up Incidence

Impact of Integrating Two Nano Based Irrigants With Two Activation Techniques in Treatment of Teeth With Acute Pulpitis on Postoperative Pain and Flare up Incidence: A Randomized Clinical Study

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 64 (estimated)
• Sponsor: Minia University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

This study aimed to evaluate and compare impact of integrating passive ultrasonic activation and laser activation with nano-chitosan and aloe vera in terms of postoperative pain and flare-up incidence in a randomized clinical trial.

Conditions

• Postoperative Pain
• Flare up
• Flare Up, Symptom

Interventions

Type	Name	Description
OTHER	Chitosan Nanoparticles Irrigant	using Chitosan Nanoparticles irrigant as a final irrigation solution.
OTHER	aloe vera nanoparticles irrigant	using Aloe Vera Nanoparticles irrigant as a final irrigation solution.
DEVICE	Diode Laser Activation	activation of nanoparticles irrigants using diode laser
DEVICE	ultrasonic activator	activation of nanoparticles irrigants using ultrasonic activator

Timeline

• Start date: 2025-09-10
• Primary completion: 2026-07-01
• Completion: 2026-08-10
• First posted: 2025-07-24
• Last updated: 2025-07-24