NCT07083947

Effect of Herbal Compositions on Body Weight, Body Composition and Metabolic Health in Overweight Subjects

A Randomized, Double-blind, Placebo-controlled Clinical Study to Evaluate the Effect of Herbal Compositions CL19183 and CL24212 on Body Weight, Body Composition and Metabolic Health in Overweight Subjects

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (actual)
• Sponsor: ApexCPG LLC · Industry
• Sex: All
• Age: 22 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The Purpose of the study is to evaluate the efficacy of herbal composition CL19183 and CL24212 on body weight, body composition and metabolic health in overweight subjects.

Detailed description

A total of 150 male and female subjects aged between 25 and 55 years will be included in the study. Assessment of inclusion and exclusion criteria will be done based on clinical and laboratory investigations. The eligible subjects will be randomized as per the computer-generated randomization list. The subjects will be assigned to either CL19183:450 mg or CL24212:300 mg or Placebo arm at 1:1:1 ratio. The subjects will be instructed to take one capsule daily in the morning after breakfast for 16 weeks. Apart from primary and secondary outcomes, the study will also record the vital signs and adverse events to evaluate the herbal composition safety and tolerability. The safety assessment of the CL19183 and CL24212 will also include routine laboratory investigations on blood, urine and clinical chemistry at screening and the final visit of the intervention

Conditions

• Healthy Participants

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	CL19183	One capsule taken orally each morning after breakfast with water for 16 weeks
DIETARY_SUPPLEMENT	CL24212	One capsule taken orally each morning after breakfast with water for 16 weeks
OTHER	Placebo	One capsule taken orally each morning after breakfast with water for 16 weeks

Timeline

• Start date: 2025-07-16
• Primary completion: 2026-01-25
• Completion: 2026-01-25
• First posted: 2025-07-24
• Last updated: 2025-12-01

Locations

1 site across 1 country: India