NCT07080853

Acute Exercise With Overdressing

Efficacy of a Novel Exercise + Overdressing Protocol to Induce Targeted Heat Stress in Temperate Environments (Acute XO-Study)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 23 (actual)
• Sponsor: United States Army Research Institute of Environmental Medicine · Federal
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine if exercise with extra clothing in a gym-like environment can increase body temperatures appropriately to help people adapt to the heat.

Detailed description

The purpose of the present study is to examine the influence of a novel 90-minute exercise + overdressing protocol on thermal responses in comparison to matched exercise in standard PT clothing. Sixteen healthy and fit adults (8 men and 8 women) will complete two 90-minute exercise sessions (randomized order) in a temperate environment (\~20°C, \~50% relative humidity, and \~1 mph air velocity) involving a 30-minute run immediately followed by a 60-minute walk. Participants will wear standard physical training (PT) clothing (shorts, t-shirt) during one session and an overdressing ensemble in the other. The investigators hypothesize that 1) exercise + overdressing will elevate core temperature to between 38.3°C and 39.3°C for at least 45 minutes; and 2) elevations in core temperature, skin temperature, heart rate, and sweat rate will be substantially larger than observed with 90 minutes of matched exercise in standard PT clothing.

Conditions

• Heat Stress, Exertional
• Heat Acclimation and Thermotolerance

Interventions

Type	Name	Description
OTHER	Exercise with Overdressing	Run for 30 minutes followed by walk for 60 minutes in a temperate (gym-like environment) wearing overdressing ensemble.
OTHER	Control Exercise	Run for 30 minutes followed by walk for 60 minutes in a temperate (gym-like environment) wearing control clothing ensemble.

Timeline

• Start date: 2023-06-22
• Primary completion: 2025-04-28
• Completion: 2025-04-28
• First posted: 2025-07-23
• Last updated: 2025-12-24

Locations

1 site across 1 country: United States