NCT07079371

Micellar Water and the Skin Barrier: Comparing Rinsing vs. Non-Rinsing Application

Assessment of the Effect of Micellar Solution on Measures of Skin Barrier Function

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: University of Split, School of Medicine · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to assess how micellar water affects the skin barrier in healthy adult volunteers. The main questions it aims to answer are: * Does leaving micellar water on the skin affect skin barrier function differently than rinsing it off? * Are there measurable differences in transepidermal water loss (TEWL), skin hydration, and erythema between the two application methods? Researchers will compare the effects of micellar water left on the skin versus rinsed off after application. Participants will: * Be randomly assigned to one of two groups * Apply micellar water to their forehead once daily for 21 days * Either leave the micellar water on or rinse it off, depending on their group * Undergo non-invasive measurements of TEWL, skin hydration, and erythema before and after the intervention

Conditions

• Effects of Micellar Water Application on Skin Barrier Integrity, Hydration, and Erythema in Healthy Skin

Interventions

Type	Name	Description
PROCEDURE	Micellar Water Application (No Rinse)	Participants apply micellar water to the forehead once daily and leave it on the skin without rinsing for 21 days.
PROCEDURE	Micellar Water Application (With Rinse)	Participants apply micellar water to the forehead once daily and rinse it off after application for 21 days.

Timeline

• Start date: 2025-06-18
• Primary completion: 2026-01-01
• Completion: 2026-01-01
• First posted: 2025-07-23
• Last updated: 2025-07-23

Locations

1 site across 1 country: Croatia