NCT07077187

Effect of Rasagiline on Balance in Parkinson's Disease as Measured by Computerized Posturography

• Status: Withdrawn
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: New York Medical College · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study evaluates the effect of rasagiline on balance in Parkinson's disease. Participants taking study medication which is rasagiline or sugar pill will undergo a computerized balance test on and off medication. Participants will stand on a platform which which moves slightly and a computer will measure their body sway and provide a balance score.

Detailed description

The study will test the hypothesis that therapy with rasagiline improves balance in PD patients as measured by computerized dynamic posturography. 5 subjects will be randomized to rasagiline or placebo and 5 further subjects will be randomized to rasagiline as adjuvant therapy versus placebo. Subjects will be analyzed by computerized dynamic posturography testing. The device measures body sway under varying visual and vestibular cues and is used for assessment of balance

Conditions

• PARKINSON DISEASE (Disorder)

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	computerized dynamic posturography	Patients in each arm will have computerized dynamic posturography performed at baseline prior to taking first tablet as well as at 4 weeks and 8 weeks. In the adjuvant therapy arm, subjects will be evaluated on rasagiline but in a functional OFF state for their other Parkinson disease medications.
DRUG	Rasagiline 1 mg capsule	Rasagiline 1 mg oral tablet daily will be administered to study participants.
DRUG	Placebo	Placebo 1 mg oral tablet daily will be administered to study participants.

Timeline

• Start date: 2014-09-15
• Primary completion: 2017-07-10
• Completion: 2017-07-10
• First posted: 2025-07-22
• Last updated: 2025-07-24

Regulatory

• FDA-regulated drug study