Trials / Completed
CompletedNCT07076745
High-Sensitive CRP and Carotid Stiffness Between Patients With and Without Coronary Slow Flow
Comparative Assessment of High Sensitive CRP and Carotid Stiffness Between Patients With and Without Coronary Slow Flow
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 60 (actual)
- Sponsor
- Sohag University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This study aims to compare the levels of high-sensitivity C-reactive protein (hs-CRP) and carotid artery stiffness between patients with coronary slow flow phenomenon (CSFP) and those with normal coronary flow.
Detailed description
The coronary slow flow phenomenon (CSFP) is characterized by delayed opacification of the coronary arteries during angiography in the absence of significant epicardial coronary artery disease. Hypothesis: High-sensitivity C-reactive protein (hs-CRP) is a well-established biomarker of systemic inflammation and has been associated with various cardiovascular conditions. Elevated hs-CRP levels have been observed in patients with CSFP, suggesting an inflammatory component in its pathogenesis. This marker not only predicts future cardiovascular events but may also reflect ongoing vascular inflammation in patients with angiographically normal coronary arteries.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | High-sensitivity C-reactive protein | High-sensitivity C-reactive protein will be done. |
| OTHER | Stiffness Measurement | Measurements will include carotid intima-media thickness (CIMT), systolic (Ds) and diastolic (Dd) diameters, and calculation of stiffness indices: * β-stiffness index. * Peterson's elastic modulus (Ep). * Distensibility coefficient (DC). * Compliance coefficient (CC). * Strain. |
Timeline
- Start date
- 2025-01-01
- Primary completion
- 2025-07-10
- Completion
- 2025-07-10
- First posted
- 2025-07-22
- Last updated
- 2025-07-22
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT07076745. Inclusion in this directory is not an endorsement.