NCT07075809

The Effectiveness of Laserpuncture on Chemotherapy-induced Leucopenia in Head and Neck Cancer Patients

The Effectiveness of Laserpuncture on Chemotherapy-induced Leucopenia and Quality of Life in Head and Neck Cancer Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Indonesia University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to evaluate if laserpuncture (laser acupuncture) can reduce leucopenia caused by chemotherapy and improve the quality of life in patients with head and neck cancer. The main questions it aims to answer are: * Does laserpuncture reduce the incidence of chemotherapy-induced Leucopenia ? * Does laserpuncture improve quality of life in these patients? Researchers will compare patients receiving laserpuncture therapy to a control group receiving sham laserpuncture to see if the intervention has a beneficial effect. Participants will: * Undergo six sessions of laserpunktur or sham laserpuncture during chemotherapy * Have leukocyte counts and absolute neutrophil counts measured before and 7-14 days after chemotherapy * Complete quality of life assessments using EORTC QLQ-C30 and EORTC QLQ-H\&N35 questionnaires

Conditions

• Leucopenia Induced Chemoteraphy Adult

Interventions

Type	Name	Description
DEVICE	The laser acupuncture	The intervention group in this study receives laser acupuncture therapy using a laser Micropad GL2+ device with an infrared wavelength of 880 nm. The laser acupuncture is applied to specific acupuncture points, namely GV14, LI4, ST36, and SP6 on the body, as well as ear points including MA-TF1 Shenmen, MA-SC5 Liver, MA-IC3 Endocrine, MA-IC8 Spleen, and MA-SC6 Kidney. Treatment is administered once daily for a total of six sessions during the chemotherapy treatment period.
DEVICE	Sham Laser acupuncture	The Control group in this study receives sham laser acupuncture therapy using a laser Micropad GL2+ device with deactivation mode. The sham laser acupuncture is applied to specific acupuncture points, namely GV14, LI4, ST36, and SP6 on the body, as well as ear points including MA-TF1 Shenmen, MA-SC5 Liver, MA-IC3 Endocrine, MA-IC8 Spleen, and MA-SC6 Kidney. Treatment is administered once daily for a total of six sessions during the chemotherapy treatment period.

Timeline

• Start date: 2025-10-01
• Primary completion: 2025-12-12
• Completion: 2025-12-12
• First posted: 2025-07-20
• Last updated: 2026-01-05

Locations

1 site across 1 country: Indonesia