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RecruitingNCT07075679

Screening Mammography: Single Reading by One Radiologist With AI vs. Double Reading by Two Radiologists (AI-BCSQ)

Use of Artificial Intelligence in Breast Cancer Screening: Impact of AI-Assisted Single Reading by One Radiologist on Screening Quality Indicators Compared to Standard Double Reading by Two Radiologists Without AI

Status
Recruiting
Phase
N/A
Study type
Interventional
Enrollment
8,000 (estimated)
Sponsor
University Hospital Olomouc · Academic / Other
Sex
Female
Age
45 Years – 69 Years
Healthy volunteers
Accepted

Summary

A randomized prospective study comparing the evaluation of mammography images in a breast cancer screening programme by a single radiologist with AI support versus standard double reading by two radiologists without AI support.

Detailed description

In the intervention group, the first reading of the screening mammogram will be performed by one radiologist with AI support. After this AI-assisted first reading is completed and recorded for the study, a standard second reading will be carried out by another radiologist. This ensures that the legal requirement for double reading in the breast cancer screening program is maintained. In the control group, mammograms will be evaluated according to the current standard practice - that is, independently by two radiologists without AI support. Participants will be divided to the two groups based on a randomization scheme that determines specific days for evaluation with AI (Group 1) and without AI (Group 2). The randomization ensures equal distribution of weekdays between the two groups to minimize bias due to variability in daily workflow, diagnostic/screening ratios, or other operational factors.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTGroup with AI iCAD version 3Reading mammograms by one radiologist with AI support
DIAGNOSTIC_TESTGroup without AIStandard double reading by two radiologists without AI.

Timeline

Start date
2025-10-06
Primary completion
2028-10-05
Completion
2028-10-05
First posted
2025-07-20
Last updated
2026-04-02

Locations

1 site across 1 country: Czechia

Source: ClinicalTrials.gov record NCT07075679. Inclusion in this directory is not an endorsement.