NCT07074821

Antimicrobial Locks for Hemodialysis Catheter Infections

Effect of Tunneled Hemodialysis Catheter Antimicrobial Lock Solution in Prevention of Catheter Related Blood Stream Infection.

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Oman Ministry of Health · Other Government
• Sex: All
• Age: 13 Years
• Healthy volunteers: Not accepted

Summary

Tunneled hemodialysis catheters are susceptible to infection with high incidence of complication to the hemodialysis patients .The study aimed to prevent catheter infection through comparing use of antimicrobial solution (Taurolidine) when used as lock solution installed in the lumen of the catheter at the end of the hemodialysis session with the usually used lock solution heparin. The Study was performed on 100 hemodialysis patients over one year in Sohar hospital ,Oman .

Conditions

• Catheter Related Blood Stream Infection
• Hemodialysis
• Vascular Access

Interventions

Type	Name	Description
DRUG	Taurolidine citrate 4% and heparin 500	Taurolidine ,citrate 4% and heparin 500 units per ml used as lock solution in tunneled hemodialysis catheter

Timeline

• Start date: 2023-03-01
• Primary completion: 2024-02-29
• Completion: 2024-07-24
• First posted: 2025-07-20
• Last updated: 2025-07-20

Locations

1 site across 1 country: Oman