NCT07074730

General Anesthesia Versus Spinal Anesthesia With Local Anesthetic Infiltration for Buccal Mucosal Graft in Urethroplasty

General Anesthesia Versus Spinal Anesthesia With Local Anesthetic Infiltration for Buccal Mucosal Graft in Urethroplasty: A Randomized Controlled Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Tanta University · Academic / Other
• Sex: Male
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

This study aims to compare general anesthesia and spinal anesthesia with local anesthetic infiltration for buccal mucosal graft (BMG) in urethroplasty.

Detailed description

Urethroplasty is a surgical procedure aimed at reconstructing the urethra and is considered the standard treatment for bulbar urethral strictures, with different types of tissues used as either grafts or flaps, affecting approximately 300 per 100,000 males. Postoperative pain following urethroplasty with buccal mucosal graft (BMG) is primarily related to the oral graft harvest site. General Anesthesia provides a state of complete unconsciousness, ensuring that patients are free from pain and awareness during the surgery. It can be beneficial in complex cases or when extended manipulation is required, allowing for muscle relaxation and controlled ventilation. On the other hand, spinal anesthesia involves the injection of anesthesia into the cerebrospinal fluid, resulting in targeted numbness in the lower body. This technique can be advantageous for its fast, simple, cost-effective method, rapid onset, lower risk of systemic complications, and preservation of airway reflexes.

Conditions

• General Anesthesia
• Spinal Anesthesia
• Local Anesthetic Infiltration
• Buccal Mucosal Graft
• Urethroplasty

Interventions

Type	Name	Description
OTHER	Spinal anesthesia	Patients will receive spinal anesthesia with local anesthetic infiltration.
OTHER	General anesthesia	Patients will receive general anesthesia.

Timeline

• Start date: 2025-07-19
• Primary completion: 2027-03-01
• Completion: 2027-03-01
• First posted: 2025-07-20
• Last updated: 2025-07-22

Locations

1 site across 1 country: Egypt