NCT07073703

Effectiveness of a Personalized 6-month Programme on Frailty in Older Patients Treated for Bladder or Kidney Cancer.

Effectiveness of a Personalized 6-month Programme on Frailty in Older Patients Treated for Bladder or Kidney Cancer - FRAGECO - Multicenter, Controlled, Randomized Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 106 (estimated)
• Sponsor: Centre Hospitalier Universitaire de Saint Etienne · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

Bladder and kidney cancers are commonly diagnosed in older adults. Surgery remains the primary treatment modality for patients with kidney or bladder cancer. In older patients, common co-morbidities include fatigue, physical deconditioning characterized by reduced cardiorespiratory fitness and progressing sarcopenia, pain- whether disease- related or treatment-induced- and undernutrition. These factors increased the risk of post-operative complications and exacerbate patient frailty. The investigators propose a personalized 6-month program both pre- and post-surgery, including adapted physical activity sessions, therapeutic education workshops, and systematic referral to the department's DAPAP program.

Conditions

• Bladder (Urothelial, Transitional Cell) Cancer
• Kidney (Renal Cell) Cancer

Interventions

Type	Name	Description
PROCEDURE	APA	2 adapted physical activity (APA) sessions per week for 4 weeks before and after surgery
BEHAVIORAL	Therapeutic education workshops	Therapeutic education workshops tailored to individual needs, covering topics as physical activity, nutrition, treatments, fatigue, and relaxation.
PROCEDURE	DAPAP	Referral to the department's DAPAP for a 12-week "bridge program", consisting of one session per week.

Timeline

• Start date: 2025-12-03
• Primary completion: 2027-09-01
• Completion: 2028-03-01
• First posted: 2025-07-18
• Last updated: 2025-12-09

Locations

2 sites across 1 country: France