NCT07073092

Propolis for Management of Chemotherapy-Induced Oral Mucositis in Pediatric Patients

Propolis for Management of Chemotherapy-Induced Oral Mucositis in Pediatric Patients: A Randomized Controlled Clinical Trial With Biochemical Analysis

• Status: Not Yet Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 2 Years – 18 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to evaluate the efficacy of propolis in the prevention of oral mucositis and reducing pain score in children undergoing chemotherapy, and assessing its impact on body mass index, pediatric quality of life and total antioxidant assay. The main question it aims to answer is: What is the effect of propolis on oral mucositis scores in children undergoing chemotherapy? Participants will: Take propolis 3 times daily for 21 days follow up weekly for 3 weeks

Conditions

• Oral Mucositis Due to Chemotherapy

Interventions

Type	Name	Description
DRUG	propolis	propolis medicated jelly candy.
DRUG	chlorohexidine mouthwash and topical antifungal	chlorohexidine mouthwash and topical antifungal

Timeline

• Start date: 2025-07-15
• Primary completion: 2025-12-30
• Completion: 2026-01-30
• First posted: 2025-07-18
• Last updated: 2025-07-18

Locations

1 site across 1 country: Egypt