NCT07071545

Effect of Regular Physical Activity in Normal-Weight Individuals With Type 2 Diabetes and Abdominal Obesity

Impact of Regular Physical Activity in Normal-Weight Individuals With Type 2 Diabetes and Abdominal Obesity: Nationwide Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 249,247 (actual)
• Sponsor: Samsung Medical Center · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Individuals with T2DM accompanied by abdominal obesity tend to experience worse clinical outcomes. To identify modifiable factors that may improve these outcomes, the investigators conducted a retrospective cohort study using data from the Korean National Health Insurance Service (K-NHIS) database to evaluate the impact of regular physical activity.

Detailed description

It is well established that patients with T2DM and abdominal obesity have worse clinical outcomes. This holds true even among individuals with a normal body weight but central (abdominal) obesity. In this study, the investigators aimed to determine whether engaging in regular physical activity (defined as vigorous exercise at least three times per week) is associated with improved clinical outcomes in normal-weight individuals with abdominal obesity. Specifically, we compared the incidence of MACCE between normal-weight patients with type 2 diabetes who had abdominal obesity and those who did not.

Conditions

• Diabetes (DM)
• Physical Activity

Interventions

Type	Name	Description
BEHAVIORAL	Regular physical activity	Moderate-to-vigorous physical activity at least three times per week.
BEHAVIORAL	No regular physical activity	The group that did not engage in physical activity according to the guidelines

Timeline

• Start date: 2010-01-01
• Primary completion: 2023-03-30
• Completion: 2023-09-30
• First posted: 2025-07-17
• Last updated: 2025-07-17