NCT07070778

Arterial Stiffness in Individuals With Breast Cancer

The Effect of Upper Extremity Aerobic Exercise Training on Arterial Stiffness in Individuals With Breast Cancer

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (estimated)
• Sponsor: Hacettepe University · Academic / Other
• Sex: Female
• Age: 40 Years – 69 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study was to evaluate vascular toxicity induced by anthracyclines and other anticancer drugs and to measure arterial stiffness in women with breast cancer and, in addition, to evaluate the acute and chronic arterial stiffness responses of upper extremity aerobic exercise training.

Detailed description

Breast cancer is the most common type of cancer in women both in the world and in our country. Today, with the technological developments, breast cancer treatments have improved considerably and the mortality rate has decreased. However, despite the developments in treatments, the quality of life of patients has still not reached the desired level. Upper extremity dysfunctions are frequently observed in patients after breast cancer treatment. This upper extremity dysfunction causes a decrease in the quality of daily life of patients. Arterial stiffness contributes to hypertension and increases the risk of cardiovascular disease. The American College of Sports Medicine (ACSM) recommends that healthy adults perform moderate to vigorous intensity aerobic exercise at least 5 times per week and resistance exercise 2-3 times per week. Aerobic exercise can reduce arterial stiffness after both acute and chronic interventions. A small number of studies on aerobic exercise have reported that this exercise training improves the functional level of patients after breast cancer. However, the effect of aerobic exercise training on arm exercise capacity and arterial stiffness in patients with breast cancer is still unclear. Thus, the results of this study may guide physiotherapists working in this field about upper extremity exercise training after breast cancer.

Conditions

• Aerobic Exercise
• Breast Cancer
• Arterial Stiffness

Interventions

Type	Name	Description
OTHER	Upper Extremity Aerobic Exercise Training Program	12 weeks of supervised upper limb aerobic exercise training, 3 sessions per week, 25 minutes per session.

Timeline

• Start date: 2025-07-08
• Primary completion: 2026-11-01
• Completion: 2026-12-01
• First posted: 2025-07-17
• Last updated: 2025-12-29

Locations

1 site across 1 country: Turkey (Türkiye)