NCT07070180

Analysis of Psychoneuroimmunological Parameters of Health in Specific Population Groups in Slovakia

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 700 (actual)
• Sponsor: Comenius University · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

This study aims to investigate the links between psychological and biological immunity from the perspective of psychology, epidemiology, and immunology in a general population study sample as well as in a specific group of people in treatment for alcohol addiction.

Detailed description

The study will explore the associations between the level of psychological immunity and the current psychological state of the participants, possible links between the level of psychological immunity in adulthood and adverse childhood experiences, and finally, the association between the psychological immunity and biological immunity expressed by the self- assessed perceived immune status and on a molecular level by quantity of cytokines and in a specific subgroup also by natural killer cells. All this will be studied in a sample of general population as well as in a specific group of people in treatment for alcohol addiction that was chosen based on the known adverse immune-related health effects of excessive alcohol consumption.

Conditions

• Immunity
• Cytokine Levels
• Psychological Adaptation
• Resilience
• Positive Thinking
• Sense of Control
• Sense of Coherence
• Self-control
• Problem Solving
• Mindfulness
• Adverse Childhood Experience
• Psychological Distress
• Stress
• Stress Response
• Depression Symptoms
• Anxiety Symptoms
• Socio-economic Status

Timeline

• Start date: 2024-01-01
• Primary completion: 2024-12-15
• Completion: 2025-12-15
• First posted: 2025-07-17
• Last updated: 2026-02-19

Locations

3 sites across 1 country: Slovakia