NCT07069933

Repurposing Itraconazole as an Adjuvant Therapy in Treatment of Patients With Acute Myeloid Leukemia: Is it a Hopeful Avenue for Enhancing Treatment Options?

"Repurposing Itraconazole as an Adjuvant Therapy in Treatment of Patients With Acute Myeloid Leukemia: Is it a Hopeful Avenue for Enhancing Treatment Options?"

• Status: Not Yet Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Mansoura University · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Accepted

Summary

A prospective, randomized, controlled, parallel clinical trial will be conducted at Clinical Oncology and Nuclear Medicine Center at Mansoura University Hospital to assess the efficacy of Itraconazole as an adjuvant therapy in treatment of patients with acute myeloid Leukemia.

Conditions

• Acute Myeloid Leukemia

Interventions

Type	Name	Description
DRUG	Standard care +itraconazole 200mg	Is an antifungal used to treat a variety of fungal infections. It belongs to a class of drugs known as azole antifungals.
DRUG	Chemotherapy	Standard Care (in control arm)

Timeline

• Start date: 2025-07-01
• Primary completion: 2025-07-01
• Completion: 2025-12-01
• First posted: 2025-07-17
• Last updated: 2025-07-17

Locations

1 site across 1 country: Egypt