NCT07068451

Greater Occipital Nerve Block Alone Versus Dual Nerve Block in Cervicogenic Headache and Occipital Neuralgia

A Prospective Randomized Study Comparing Greater Occipital Nerve Block Alone Versus Dual Nerve Blockade in the Management of Cervicogenic Headache and Occipital Neuralgia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 160 (actual)
• Sponsor: Tishreen University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study looked at two types of nerve block injections used to treat people with cervicogenic headache (CEH) and occipital neuralgia (ON)-two painful conditions that often cause pain at the back of the head and neck. The injections target nerves in the upper neck that may be causing the pain. The researchers compared: One nerve injection (greater occipital nerve block, or GONB), versus Two nerve injections (GONB plus lesser occipital nerve block, or LONB).

Conditions

• Ervicogenic Headache (CEH)
• Occipital Neuralgia (ON)

Interventions

Type	Name	Description
PROCEDURE	Greater Occipital Nerve Block (GONB)	A landmark-guided injection of 1 mL of 2% lidocaine administered at the anatomical location of the greater occipital nerve (GON) to treat cervicogenic headache and occipital neuralgia. Performed without corticosteroids or imaging guidance.
PROCEDURE	Combined Greater and Lesser Occipital Nerve Block (GONB + LONB)	Two landmark-guided injections of 1 mL of 2% lidocaine each at the anatomical locations of the greater and lesser occipital nerves. Performed without corticosteroids or imaging, targeting broader nerve involvement in cervicogenic headache and occipital neuralgia.

Timeline

• Start date: 2020-01-01
• Primary completion: 2023-04-01
• Completion: 2023-04-01
• First posted: 2025-07-16
• Last updated: 2025-07-16

Locations

1 site across 1 country: Syria