NCT07064577

Novel ROS-scavenging Nanoenzymes for the Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: West China Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

There is no standard treatment for radiation dermatitis. In this study, the investigators have designed novel ROS-scavenging nanoenzymes and aim to evaluate their effectiveness in preventing radiation dermatitis in patients with head and neck cancer.

Detailed description

Radiotherapy often leads to various complications, with radiation dermatitis being the most common side effect observed in the majority of tumor patients undergoing treatment. This condition not only affects a patient's appearance but, in severe cases, may even require the interruption of treatment. Currently, there is no standard treatment for radiation dermatitis. In this study, the investigators have designed novel ROS-scavenging nanoenzymes, offering a potential new approach for preventing and treating radiation dermatitis. This clinical trial aims to evaluate the effectiveness of these novel ROS-scavenging nanoenzymes in preventing radiation dermatitis in patients with head and neck cancer.

Conditions

• Radiation Dermatitis

Interventions

Type	Name	Description
DRUG	ROS-scavenging Nanoenzymes	ROS-scavenging nanoenzymes are applied to the treatment area, once daily during radiotherapy.
BEHAVIORAL	Standard of care	Standard of care

Timeline

• Start date: 2025-07-15
• Primary completion: 2025-09-15
• Completion: 2025-10-15
• First posted: 2025-07-14
• Last updated: 2025-08-07

Locations

1 site across 1 country: China