NCT07064187

Evaluate The Improvement In Symptoms Of Patients Using Cationorm After Pterygium Surgery

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Nguyen Viet Giap · Academic / Other
• Sex: All
• Age: 35 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The goal of this interventional clinical trial is to learn whether Cationorm can improve symptoms after pterygium surgery. The main question it aims to answer is what is the level of improvement of symptoms after pterygium surgery. Researchers will compare with other artificial tears (hyaluronic acid, polymers or cellulose derivatives eye drops) arm to see if Cationorm is similar or superior in terms of improvement of symptoms after pterygium surgery. Participants will * Take 1 drop Cationorm/artificial tear before and after surgery and during follow up. * Visit for checkups after 7 days

Detailed description

Participants will take: * Before surgery: 1 drop Cationorm/artificial tear at the eye that will undergo surgery * After surgery: 1 drop Cationorm/artificial tear at the eye that underwent surgery before eye bandages * Follow up after surgery: 1 drop Cationorm/artificial tear 4-6 times/day alternating with antibiotics (third-fourth generation quinolone) with 2-hour interval between drops * Maintenance phase: 7-14 days with the same regimen * After day 5, if fluorescein staining (-), can add corticosteroid monotherapy or addition with antibiotics * After 5 days of surgery, can add more antibiotics depend on the symptoms of patients

Conditions

• Ocular Discomfort

Interventions

Type	Name	Description
DRUG	Cationorm single-dose eye drop	Cationorm single-dose eye drop is a preservative-free, cationic oil-in-water nano-emulsion.
DRUG	Artificial tear eye drop	Artificial tear eye drops are hyaluronic acid, polymers or cellulose derivatives eye drops

Timeline

• Start date: 2022-06-15
• Primary completion: 2022-08-15
• Completion: 2022-08-15
• First posted: 2025-07-14
• Last updated: 2025-08-06

Locations

1 site across 1 country: Vietnam