Trials / Active Not Recruiting
Active Not RecruitingNCT07063550
Microplastics in Paraneoplastic and Intratumoral for Colorectal Cancer
Identification of Paraneoplastic and Intratumoral Microplastics in Colorectal Cancer and Their Association Analysis With Macrogenomics and Metabolomics
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- Dong Peng · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The objective of this study is to identify and characterize microplastics present in peritumoral and intratumoral tissues of colorectal cancer patients, and to investigate their associations with gut microbiome composition and metabolic profiles. By integrating microplastic analysis with metagenomic and metabolomic data, we aim to explore the potential impact of environmental microplastic exposure on tumor microenvironment alterations, microbial dysbiosis, and metabolic reprogramming in colorectal cancer.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | exposure to microplastic | Microplastic content in cancerous and paracancerous tissues |
Timeline
- Start date
- 2024-12-01
- Primary completion
- 2026-10-01
- Completion
- 2026-12-31
- First posted
- 2025-07-14
- Last updated
- 2025-07-14
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT07063550. Inclusion in this directory is not an endorsement.