NCT07063511

Pan-Facial Layering of Hyaluronic Acid Filler

A Prospective Clinical Trial Evaluating the Safety and Efficacy of Concurrently Layering Hyaluronic Acid Fillers in Different Tissue Planes During Facial Aesthetic Treatments

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Erevna Innovations Inc. · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Recent advancements in anatomical studies have enabled a more sophisticated approach to treating patients with facial aesthetic concerns with hyaluronic acid (HA) fillers. For instance, volumizing a specific area of concern may be warranted, but it is essential to understand how the underlying patient anatomy is continuing to laxity and hollowness. Varying manufacturing technology have offered a range of HA fillers with different physical and chemical properties adapted to different indications, each one tailored to provide a slightly different outcome based on the needs of the patient. Given these advances in the medical aesthetic field, investigators and clinicians are seeking to develop a new methodology for providing patients with a more tailored and personalized treatment approach. This methodology includes using a pan-facial, multilayering treatment technique that can be employed by injectors once experience is gained with standard techniques. The goal of this study is to assess the efficacy and safety of layering HA from the Restylane line of soft tissue products to create a more harmonious and complete aesthetics results.

Conditions

• Aesthetic

Interventions

Type	Name	Description
DEVICE	Restylane Injectables	Participants will receive multilayering treatment (i.e., one product will be placed deep and one in a more superficial plane) in area of primary deficit (i.e., the midface or lower face), in isolation or combination with other treatment areas.

Timeline

• Start date: 2025-07-02
• Primary completion: 2026-07-02
• Completion: 2026-08-02
• First posted: 2025-07-14
• Last updated: 2025-09-22

Locations

1 site across 1 country: Canada