NCT07059195

Non-Invasive Techniques to Maintain Neck Flexion and Reduce Anastomotic Tension After Tracheal Resection

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 6 Months – 80 Years
• Healthy volunteers: Not accepted

Summary

Tracheal surgery represents a relatively recent advancement in the field of thoracic surgery. The trachea has unique anatomical and physiological challenges that historically rendered surgical manipulation both risky and limited. Early interventions involving the trachea were primarily restricted to emergency tracheostomy procedures, typically performed as life-saving measures during acute airway obstruction (1). Attempts at tracheal reconstruction were largely unsuccessful due to the absence of suitable anesthesia, inadequate surgical tools, and the prevailing belief that tracheal cartilage lacked sufficient regenerative. As a result, tracheal resection and reconstruction were long considered unfeasible (2). The modern era of tracheal surgery began to take shape in the mid-20th century. While early attempts at tracheal resection were performed with limited success, it was the pioneering work of Dr. Hermes C. Grillo in the 1960s that truly transformed the field. Through systematic study of tracheal anatomy, vascular supply, and biomechanics, Dr. Grillo developed standardized and safe techniques for segmental tracheal resection followed by primary end-to-end anastomosis. His work demonstrated that segmental resection of the trachea followed by primary end-to-end anastomosis was feasible and safe (3)(4).

Conditions

• Maintain Neck Flexion and Reduce Anastomotic Tension After Tracheal Resection

Interventions

Type	Name	Description
PROCEDURE	cervical collar or cervical-thoracic orthosis.	postoperative cervical spine flexion maintained using non-invasive techniques, such as a cervical collar or cervical-thoracic orthosis.
DEVICE	chin-to-chest (Grillo) suturing	cervical spine flexion maintained using traditional chin-to-chest (Grillo) suturing

Timeline

• Start date: 2025-06-30
• Primary completion: 2027-06-30
• Completion: 2027-06-30
• First posted: 2025-07-10
• Last updated: 2025-07-10

Locations

1 site across 1 country: Egypt