NCT07058727

Different Hemostatic Agents Used in Partial Pulpotomy on Pulp Survival and Postoperative Pain

The Effect of Different Hemostatic Agents Used in Partial Pulpotomy on Pulp Survival and Postoperative Pain: A Randomized Clinical Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 75 (estimated)
• Sponsor: Cukurova University · Academic / Other
• Sex: All
• Age: 15 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

This randomized clinical trial evaluates the efficacy of sodium hypochlorite (NaOCl), chlorhexidine (CHX), and cold saline as hemostatic agents in partial pulpotomy. The study compares postoperative pain (via VAS scores) and pulp survival (via clinical/radiographic evaluation) at 1, 3, 7 days, 6 months, and 12 months

Conditions

• Efficacy of Hemostatic Agents
• Partial Pulpotomy
• Postoperative Pain

Interventions

Type	Name	Description
DRUG	Sodium Hypochlorite 2,5%	2.5% NaOCl applied for 1 min to exposed pulp for hemostasis, followed by standard pulp capping
DRUG	Chlorhexidine	2% CHX applied for 1 min to achieve hemostasis, with identical subsequent steps to NaOCl group
DRUG	Cold Saline	Hemostasis via 4°C saline (1 Min), then standardized pulp capping

Timeline

• Start date: 2025-05-01
• Primary completion: 2025-11-01
• Completion: 2026-05-01
• First posted: 2025-07-10
• Last updated: 2026-04-01

Locations

1 site across 1 country: Turkey (Türkiye)