Trials / Enrolling By Invitation
Enrolling By InvitationNCT07056738
Prospective Exploratory Cohort Study on Ganglion Cell Degeneration in Retinitis Pigmentosa Patients
Longitudinal Characterization of Inner Retina Health in Low Vision Retinitis Pigmentosa Patients to Optimize Retinal Ganglion Cell-based Optogenetic Vision Restoration Therapy
- Status
- Enrolling By Invitation
- Phase
- —
- Study type
- Observational
- Enrollment
- 130 (estimated)
- Sponsor
- University Medical Center Goettingen · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study is an explorative prospective observation of retinal ganglion cell degeneration and/or inner retina degeneration in Retinitis pigmentosa patients. The rate and patterns of progression will be correlated to the outer retina layers as well as clinical and genetic data of patients. Secondary goal is to determine potential parameters for optogenetic treatment eligibility.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | imaging | OCT, OCTA, RNFL-OCT, fundus autofluorescence, fundus imaging, flaremeter, fundus and slit lamp examination |
Timeline
- Start date
- 2025-03-01
- Primary completion
- 2030-03-01
- Completion
- 2030-04-01
- First posted
- 2025-07-09
- Last updated
- 2025-07-09
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT07056738. Inclusion in this directory is not an endorsement.