NCT07056257

Adjunct Use of Diode Laser Therapy and Omega 3 Gel in Local Drug Delivery Approach on The Treatment of Localized Aggressive Periodontitis

The Effect of Adjunct Use of Diode Laser Therapy and Omega 3 Gel in Local Drug Delivery Approach on The Treatment of Localized Aggressive Periodontitis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (actual)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate and compare the effect of combination therapy between diode laser and omega3 gel in the local drug delivery approach as an adjunct to scaling and root planning on the management of localized aggressive periodontitis clinically and immunologically.

Detailed description

Periodontitis is a disease of the periodontium occurring in an otherwise healthy adolescent, which is characterized by a rapid loss of alveolar bone about more than one tooth of the permanent dentition. The laser approach is an efficient and atraumatic technique to enhance its use for periodontal treatment. Within the limits of scientific data, treatment with diode laser and SRP showed a higher effect than SRP or laser alone. Omega3 Polyunsaturated fatty acids (PUFA) have well recognized anti-inflammatory properties. They decrease inflammation through multiple pathways.

Conditions

• Diode Laser Therapy
• Omega 3
• Localized Aggressive Periodontitis

Interventions

Type	Name	Description
PROCEDURE	Scaling-root planning (SRP)	Thirteen sites \[scaling-root planning (SRP)\] were used as a control group.
PROCEDURE	Scaling-root planning (SRP)+ laser therapy	Thirteen sites \[scaling-root planning (SRP)+ laser therapy with application of methyl cellulose gel at repeated times weekly for one month\].
PROCEDURE	Scaling-root planning (SRP)+ omega 3 gel	Thirteen sites \[scaling-root planning (SRP) + omega 3 gel repeated time weekly for one month\].
PROCEDURE	Scaling-root planning (SRP)+ laser therapy+ omega 3 gel	Thirteen sites \[combination therapy between scaling-root planning (SRP) + laser + omega 3 gel in repeated time weekly for one month\].

Timeline

• Start date: 2022-05-08
• Primary completion: 2024-04-21
• Completion: 2025-03-07
• First posted: 2025-07-09
• Last updated: 2025-07-09

Locations

1 site across 1 country: Egypt