NCT07052630

Patient Navigation and the Planning Advance Care Together Website to Improve Goals of Care Conversations in Hematopoietic Cell Transplant Survivors, IMPACT-HCT Trial

Improving Goals of Care Conversations With Hematopoietic Cell Transplant Survivors (IMPACT - HCT)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Fred Hutchinson Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This clinical trial evaluates the impact of patient navigation and the Planning Advance Care Together (PACT) website, either alone or in combination with one another, on advanced care planning (ACP) in patients with blood cancers who received a hematopoietic cell transplant (HCT). Engagement in ACP, including having goals of care conversations, improves quality of care at the end of life and supporting this should be included in all cancer survivorship care. Patient navigation is a healthcare service that is designed to guide a patient through the healthcare system and reduce barriers to timely screening follow-up, diagnosis, treatment, and supportive care. PACT is a web-based tool that provides information about ACP, assistance with documents for advanced directives, a supportive network and a forum for discussions about ACP. Patients who engage in ACP are more likely to have higher quality of life at the end of life, receive the care they want, die where they prefer, utilize hospice effectively, and are less likely to receive futile, aggressive care at the end of life. For HCT survivors at ongoing risk of death and other disease-related complications, having a plan in place for care they want is critical. Patient navigation and/or the PACT website may improve ACP, including completion of advance care directives and goals of care conversations, in patients with blood cancers who received an HCT.

Detailed description

OUTLINE: Patients are randomized to 1 of 4 conditions. CONDITION 1 (PACT + PATIENT NAVIGATION): Patients interact with the PACT website over 4 weeks and receive a navigation session over 30-45 minutes with a trained health coach to review ACP. CONDITION 2 (PATIENT NAVIGATION ONLY): Patients receive a navigation session over 30-45 minutes with a trained health coach to review ACP. CONDITION 3 (PACT ONLY): Patients interact with the PACT website over 4 weeks. CONDITION 4 (NO PACT/NO PATIENT NAVIGATION): Patients receive standard/usual care for 4 weeks on study. After completion of study intervention, patients are followed up at 4 and 12 weeks.

Conditions

• Hematopoietic and Lymphatic System Neoplasm

Interventions

Type	Name	Description
OTHER	Internet-Based Intervention	Interact with PACT website
BEHAVIORAL	Patient Navigation	Receive a patient navigation session
OTHER	Best Practice	Receive standard/usual care
OTHER	Survey Administration	Ancillary studies

Timeline

• Start date: 2025-10-21
• Primary completion: 2026-05-31
• Completion: 2026-07-31
• First posted: 2025-07-04
• Last updated: 2026-01-14

Locations

1 site across 1 country: United States