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Not Yet RecruitingNCT07049653

Anifrolumab Pregnancy Study

A Non-Interventional Multi-Database Post-Authorisation Study to Assess Pregnancy-Related Safety Data From Women With SLE Exposed to Anifrolumab

Status
Not Yet Recruiting
Phase
Study type
Observational
Enrollment
627 (estimated)
Sponsor
AstraZeneca · Industry
Sex
Female
Age
18 Years – 130 Years
Healthy volunteers
Not accepted

Summary

This is a non-interventional multi-database post-authorisation study to assess pregnancy-related safety data from women with SLE exposed to Anifrolumab.

Detailed description

The aim of this study is to describe congenital malformations, adverse pregnancy and birth outcomes in pregnancies/offspring from women with moderate/severe SLE exposed to anifrolumab during pregnancy and to compare with outcomes in women with moderate/severe SLE who are exposed to other standard of care but not anifrolumab. Adverse outcomes related to infant growth up to one year of age will also be investigated.

Conditions

Timeline

Start date
2026-01-31
Primary completion
2030-12-10
Completion
2030-12-10
First posted
2025-07-03
Last updated
2025-08-15

Source: ClinicalTrials.gov record NCT07049653. Inclusion in this directory is not an endorsement.