NCT07046312

Right Ventricular Strain in Detecting Subclinical Right Ventricular Systolic Dysfunction in Psoriatic Arthritis Patients: Relation to Serum Endostatin Level

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 20 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The aim is to assess early right ventricular systolic dysfunction in psoriatic arthritis patients using RV strain echocardiography

Detailed description

Previous studies evaluated RV strain for detection of subclinical RV affection due to PAH in systemic lupus erythematosus. However , to our knowledge , the study of RV strain and its possible association with serum endostatin to detect subclinical right ventricular systolic dysfunction and its relation to PAH in PsA patient is still a novel. Our aim is to assess early right ventricular systolic dysfunction in psoriatic arthritis patients using RV strain Echocardiography. To evaluate serum endostatin as an objective biomarker for Pulmonary arterial hypertension.

Conditions

• Psoriatic Arthritis (PsA)
• Subclinical Right Ventricular Systolic Dysfunction

Timeline

• Start date: 2025-07-01
• Primary completion: 2027-04-01
• Completion: 2027-04-01
• First posted: 2025-07-01
• Last updated: 2025-07-01

Locations

1 site across 1 country: Egypt