NCT07045987

Exploration and Establishment of an Early Warning System for Futile Reperfusion - A I S

FUtile Reperfusion in acuTe iscHEmic stRoke- FURTHER

• Status: Enrolling By Invitation
• Phase: —
• Study type: Observational
• Enrollment: 2,000 (estimated)
• Sponsor: Xijing Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this prospective cohort registration study is to establish an early warning system for futile recanalization in acute ischemic stroke by analyzing multi-omics information to identify key regulatory nodes and target molecules in ineffective recanalization. The core issue addressed by this research is: Identifying key regulatory nodes and target molecules closely associated with futile recanalization, revealing the interactions among the neurovascular unit, peripheral immune cells, and the brain lymphatic system, as well as developing early diagnostic biomarkers and novel diagnostic technologies for futile recanalization.

Conditions

• Acute Ischemic Stroke (AIS)
• Endovascular Thrombectomy
• Neurovascular Unit- Brain Lymphatic System

Timeline

• Start date: 2025-06-01
• Primary completion: 2028-05-31
• Completion: 2029-05-31
• First posted: 2025-07-01
• Last updated: 2025-07-01

Locations

1 site across 1 country: China